Hanadi Saleh Al Yafei graduated with a BA in Mass Communications with honours from the Higher College of Technology in Dubai. She started her professional career at Dubai Ladies Club and moved to Sharjah Ladies Club where she worked in Marketing and Sponsorship for six years.

In 2013, Her Highness Sheikha Jawaher bint Mohammed Al Qasimi, Chairperson of the Supreme Council for Family Affairs (SCFA), appointed Al Yafei as Department Director at SCFA and Director of the Child Safety Campaign. In 2018, Her Highness announced the establishment of the Child Safety Department, with Al Yafei appointed as its Director.

She is a member of the Child Protection Higher Committee at the Ministry of Interior and the Steering Committee of the Sharjah Child Friendly City Project, a d the National Bullying Prevention Committee.

In 2017, she obtained a Professional Diploma in Child Protection with honours from the University of Sharjah. She is currently studying to obtain an Executive MBA at the University of Sharjah.